Radiographic patterns of opportunistic lung infections and Kaposi sarcoma in homosexual men.

Important note: Information in this article was accurate in 1983. The state of the art may have changed since the publication date.

Radiographic patterns of opportunistic lung infections and Kaposi sarcoma in homosexual men.

AJR Am J Roentgenol. 1982 Oct;139(4):653-8. Unique Identifier : AIDSLINE MED/83019382
McCauley DI; Naidich DP; Leitman BS; Reede DL; Laubenstein L

Abstract: Thirty patients with lung involvement with Pneumocystis carinii and other opportunistic organisms, many of whom also had Kaposi sarcoma, were seen from December 1980 through March 1982. Clinical manifestations consisted of a prodrome of weeks to months with weight loss, fever, and malaise. When clinical pneumonia became apparent, four distinct radiographic patterns were identified. Pneumocystis carinii was uniformly present, and the most common pattern encountered was a relatively symmetric, homogeneous perihilar pneumonia that progressed to diffuse consolidation. Asymmetric and focal infiltrates were seen in patients who proved to have concomitant opportunistic infection, most commonly fungal in all but two cases. A third pattern of nodular and linear densities with or without adenopathy was seen in patients without pneumonia who had biopsy-positive Kaposi sarcoma involving the lung parenchyma. A fourth pattern represented a combination of any of the first three, and these patients had multiple infections as well as Kaposi sarcoma in the lung. Any significant change in the radiograph indicating progression of disease while on therapy prompted a rebiopsy, and in five of 10 patients other infections and/or Kaposi sarcoma were identified.

Keywords: Adult *Homosexuality Human Lung Diseases, Fungal/IMMUNOLOGY/RADIOGRAPHY Lung Neoplasms/IMMUNOLOGY/*RADIOGRAPHY Male Middle Age Pneumonia/IMMUNOLOGY/RADIOGRAPHY Pneumonia, Pneumocystis carinii/IMMUNOLOGY/*RADIOGRAPHY Sarcoma, Kaposi's/IMMUNOLOGY/*RADIOGRAPHY T-Lymphocytes/IMMUNOLOGY JOURNAL ARTICLE

830130
M8310012

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