Opportunistic infection in previously healthy women. Initial manifestations of a community-acquired cellular immunodeficiency. NLM AIDSLINE Important note: Information in this article was accurate in 1983. The state of the art may have changed since the publication date.

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Opportunistic infection in previously healthy women. Initial manifestations of a community-acquired cellular immunodeficiency.

Ann Intern Med. 1982 Oct;97(4):533-9. Unique Identifier : AIDSLINE MED/83020788
Masur H; Michelis MA; Wormser GP; Lewin S; Gold J; Tapper ML; Giron J; Lerner CW; Armstrong D; Setia U; Sender JA; Siebken RS; Nicholas P; Arlen Z; Maayan S; Ernst JA; Siegal FP; Cunningham-Rundles S

Abstract: Opportunistic infections and unusual tumors have been reported in an unprecedented outbreak of community-acquired cellular immune deficiency among homosexual and drug-abusing men. We report five women with the same syndrome. The women were residents of metropolitan New York City closely associated with drug abuse either by personal use (our patients) or close sexual contact with an abuser (one patient). One patient was bisexual. All five patients developed Pneumocystis carinii pneumonia as well as combinations of other opportunistic infections including oral candida, disseminated mycobacteria, and ulcerative herpes simplex infections. All patients had marked depression of cellular immune function. Three patients died. The appearance of this syndrome in women has important implications with regard to the epidemiology and etiology of this emerging syndrome.
Keywords: Acquired Immunodeficiency Syndrome/*IMMUNOLOGY Adult Candidiasis, Oral/IMMUNOLOGY Female Herpes Simplex/IMMUNOLOGY *Homosexuality Human Immunity, Cellular Mycobacterium avium Mycobacterium Infections/IMMUNOLOGY New York City Pneumonia, Pneumocystis carinii/*IMMUNOLOGY *Substance Abuse Syndrome JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/KWDimmunologyadultcandidiasis,oral/immunologyfemaleherpessimplex/immunologyKWDhomosexualityhumanimmunity,cellularmycobacteriumaviummycobacteriuminfections/immunologynewyorkcitypneumonia,pneumocystiscarinii/KWDimmunologyKWDsubstanceabusesyndromejournalarticle
830130
M8310009

Copyright © 1983 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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