The current outbreak of Kaposi's sarcoma and opportunistic infections. NLM AIDSLINE Important note: Information in this article was accurate in 1983. The state of the art may have changed since the publication date.

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The current outbreak of Kaposi's sarcoma and opportunistic infections.

CA Cancer J Clin. 1982 Nov-Dec;32(6):330-9. Unique Identifier : AIDSLINE MED/83024454
Haverkos HW; Curran JW

Abstract: The data suggest that: The recent outbreak of KS and PCP is a single epidemic, that of immunosuppression among homosexual men and drug abusers. The public health significance of this epidemic is probably underestimated, and clinicians should be alert to more subtle indications of immunosuppression, such as nonfatal opportunistic infections, unexplained lymphadenopathy, or other tumors. Opportunities to clarify the relationships between the environment, immunology, cancer, and infections make this outbreak scientifically important. The sudden and highly focal occurrence of these illnesses among homosexual men and drug addicts suggests a potential for their prevention if risk factors or etiologic agent(s) can be identified. The staggering morbidity and mortality associated with this outbreak dictate immediate concerted efforts to identify risk factors.
Keywords: Adolescence Adult Biopsy Comparative Study *Disease Outbreaks Female *Homosexuality Human Immune Tolerance Male Middle Age Pentamidine/THERAPEUTIC USE Pneumonia, Pneumocystis carinii/COMPLICATIONS/DRUG THERAPY/ *EPIDEMIOLOGY Recurrence Sarcoma, Kaposi's/COMPLICATIONS/*EPIDEMIOLOGY Sex Factors Skin Neoplasms/COMPLICATIONS/*EPIDEMIOLOGY Substance Abuse United States JOURNAL ARTICLE

KWDadolescenceadultbiopsycomparativestudyKWDdiseaseoutbreaksfemaleKWDhomosexualityhumanimmunetolerancemalemiddleagepentamidine/therapeuticusepneumonia,pneumocystiscarinii/complications/drugtherapy/KWDepidemiologyrecurrencesarcoma,kaposi's/complications/KWDepidemiologysexfactorsskinneoplasms/complications/KWDepidemiologysubstanceabuseunitedstatesjournalarticle
830228
M8320009

Copyright © 1983 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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