Experimental transmission of macaque AIDS by means of inoculation of macaque lymphoma tissue. NLM AIDSLINE Important note: Information in this article was accurate in 1983. The state of the art may have changed since the publication date.

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Experimental transmission of macaque AIDS by means of inoculation of macaque lymphoma tissue.

Lancet. 1983 Sep 10;2(8350):599-602. Unique Identifier : AIDSLINE MED/83296381
Letvin NL; Aldrich WR; King NW; Blake BJ; Daniel MD; Hunt RD

Abstract: Acquired immuno-deficiency syndrome (AIDS) of macaques, an animal model for human AIDS, was transmitted to previously healthy macaque monkeys by means of inoculation of either tissue or a cell-free filtrate of a macaque lymphoma. The recipients showed evidence of profound lymphocyte dysfunction or died with infections from such opportunistic agents as Candida albicans, Cryptosporidium, and cytomegalovirus.
Keywords: Acquired Immunodeficiency Syndrome/COMPLICATIONS/TRANSMISSION/ *VETERINARY Animal Candidiasis/ETIOLOGY Cytomegalovirus Infections/ETIOLOGY Disease Models, Animal Female Intestinal Neoplasms/TRANSMISSION Lymphoma/TRANSMISSION/*VETERINARY Macaca/*MICROBIOLOGY Macaca fascicularis/*MICROBIOLOGY Macaca mulatta/*MICROBIOLOGY Male Monkey Diseases/*TRANSMISSION Neoplasms, Experimental/TRANSMISSION Support, U.S. Gov't, P.H.S. T-Lymphocytes/IMMUNOLOGY JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/complications/transmission/KWDveterinaryanimalcandidiasis/etiologycytomegalovirusinfections/etiologydiseasemodels,animalfemaleintestinalneoplasms/transmissionlymphoma/transmission/KWDveterinarymacaca/KWDmicrobiologymacacafascicularis/KWDmicrobiologymacacamulatta/KWDmicrobiologymalemonkeydiseases/KWDtransmissionneoplasms,experimental/transmissionsupport,uKWDsKWDgov't,pKWDhKWDsKWDt-lymphocytes/immunologyjournalarticle
831230
M83C0010

Copyright © 1983 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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