Antibodies to cell membrane antigens associated with human T-cell leukemia virus in patients with AIDS. NLM AIDSLINE Important note: Information in this article was accurate in 1983. The state of the art may have changed since the publication date.

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Antibodies to cell membrane antigens associated with human T-cell leukemia virus in patients with AIDS.

Science. 1983 May 20;220(4599):859-62. Unique Identifier : AIDSLINE MED/83197365
Essex M; McLane MF; Lee TH; Falk L; Howe CW; Mullins JI; Cabradilla C; Francis DP

Abstract: The acquired immune deficiency syndrome (AIDS), which has recently occurred at increasing rates in homosexual men, intravenous drug users, and others, is characterized by the development of Kaposi's sarcoma and several opportunistic infections including pneumonia caused by Pneumocystis carinii. Serum samples from patients with AIDS and from matched and unmatched control subjects were examined for the presence of antibodies to cell membrane antigens associated with human T-cell leukemia virus. Nineteen of 75 of the AIDS patients had antibodies directed to surface antigens of Hut 102, a reference T lymphoid cell line infected with leukemia virus, as did two of the 336 control subjects.
Keywords: Acquired Immunodeficiency Syndrome/ETIOLOGY/IMMUNOLOGY/ *MICROBIOLOGY Animal Antibodies, Viral/*ANALYSIS Antigens, Viral/IMMUNOLOGY Female Fluorescent Antibody Technique Human Lymphatic Diseases/IMMUNOLOGY Male *Retroviridae/IMMUNOLOGY Support, Non-U.S. Gov't Support, U.S. Gov't, P.H.S. T-Lymphocytes/MICROBIOLOGY Tumor Virus Infections/COMPLICATIONS/IMMUNOLOGY/*MICROBIOLOGY JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/etiology/immunology/KWDmicrobiologyanimalantibodies,viral/KWDanalysisantigens,viral/immunologyfemalefluorescentantibodytechniquehumanlymphaticdiseases/immunologymaleKWDretroviridae/immunologysupport,non-uKWDsKWDgov'tsupport,uKWDsKWDgov't,pKWDhKWDsKWDt-lymphocytes/microbiologytumorvirusinfections/complications/immunology/KWDmicrobiologyjournalarticle
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M8380022

Copyright © 1983 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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