Immunodeficiency in female sexual partners of men with the acquired immunodeficiency syndrome. NLM AIDSLINE Important note: Information in this article was accurate in 1983. The state of the art may have changed since the publication date.

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Immunodeficiency in female sexual partners of men with the acquired immunodeficiency syndrome.

N Engl J Med. 1983 May 19;308(20):1181-4. Unique Identifier : AIDSLINE MED/83192302
Harris C; Small CB; Klein RS; Friedland GH; Moll B; Emeson EE; Spigland I; Steigbigel NH

Abstract: Because the current outbreak of acquired immunodeficiency syndrome (AIDS) among previously healthy adults may be caused by a transmissible biologic agent, and because it may be preceded by immunologic abnormalities with or without a prodromal illness, we studied seven female sexual partners of male patients with the syndrome. The male patients were all drug abusers. One of the seven women was found to have the full-blown syndrome, a second had an illness consistent with the prodrome of AIDS (generalized lymphadenopathy, lymphopenia, and a decreased ratio of helper to suppressor T cells), and four others had generalized lymphadenopathy or lymphopenia, with or without a decreased ratio of helper to suppressor T cells. Only one woman had no abnormalities. These findings suggest that AIDS may be transmitted between heterosexual men and women.
Keywords: Acquired Immunodeficiency Syndrome/DIAGNOSIS/IMMUNOLOGY/ *TRANSMISSION Adult Coitus Female Human Immunoglobulins/ANALYSIS Male Substance Abuse/COMPLICATIONS Support, U.S. Gov't, P.H.S. T-Lymphocytes, Helper-Inducer/IMMUNOLOGY T-Lymphocytes, Suppressor-Effector/IMMUNOLOGY JOURNAL ARTICLE

KWDacquiredimmunodeficiencysyndrome/diagnosis/immunology/KWDtransmissionadultcoitusfemalehumanimmunoglobulins/analysismalesubstanceabuse/complicationssupport,uKWDsKWDgov't,pKWDhKWDsKWDt-lymphocytes,helper-inducer/immunologyt-lymphocytes,suppressor-effector/immunologyjournalarticle
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M8380016

Copyright © 1983 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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