Cancer Bull; 34(2):72-74 1982. Unique Identifier : AIDSLINE ICDB/82621641
Mansell PW; Div. Cancer Prevention, M. D. Anderson Hosp. and Tumor Inst.,; Houston, TX
The pathobiology of Kaposi s sarcoma and the recent outbreak of the disease (greater than 200 cases) that has occurred among young male homosexuals are described. Kaposi s sarcoma may be associated with the DNA virus cytomegalovirus . It is also associated with immunosuppression and
Smith JH; Nichols MM; Goldman AS; Schmalstieg FC; Goldblum RM
Opportunistic infections, often fatal, are frequent concomitants of congenital and acquired immunodeficiencies. The authors report a case of fatal cryptococcosis in a 5-month-old male infant with severe combined immunodeficiency. The anatomic distribution of cryptococcal lesions suggests that the terminal small intest
High risk groups of infants with regard to sepsis are described. The first high risk group includes newborn babies, infants of the first 3 months of age, premature babies, the second babies with congenital defects of the immune system (classified and unclassified defects), the third babies with acquired immune deficie
True reference values (TRV) should ultimately be determined in blood from inactive, unstimulated rats but in practice, acceptable reference values (ARV) may be established using blood from decapitated or anesthetized animals if one is cognizant of variations associated with blood sampling procedures. Data reported her
Rev Fr Mal Respir. 1982;10(1):31-43. Unique Identifier : AIDSLINE MED/82198881
Perrin-Fayolle M
This study is in two parts. The first is devoted to a brief reminder of those situations in which pathogenic microbes invade the respiratory tract and is concerned with: the rapid elimination of the pathogen, thanks to the intervention of the first line of defence of the lung; a delayed elimination which sets in actio
A young, former homosexual, and narcotics-abusing male patient developed malaise, fever, lymphadenopathy, esophageal candidiasis, lymphopenia, and anergy progressing to severe odynophagia and a weight loss of 60 lb. Repeated endoscopic examinations revealed a progressively enlarging giant esophageal ulcer. Rigid endos
Extrachromosomal DNA was isolated from tissue culture cells that were acutely infected with simian sarcoma virus (SSV) and its associated helper (simian sarcoma-associated virus [SSAV]). Two sizes of closed circular viral genomic DNA intermediates were isolated, cleaved at the single EcoRI site, and ligated to the Cha
We sought to identify the species of origin of the cell-derived (sis) sequences of simian sarcoma virus. A molecular clone comprised of sis DNA detected related nucleotide sequences at low copy numbers in normal cellular DNAs of species as diverse as humans and quail. The extent of hybridization and degree of base-pai
Pneumocystis carinii pneumonia is a well known opportunistic infection whose radiographic presentation and association with cytomegalovirus ( CMV ) have been well described. Recently nine young homosexual men with chronic fluli
A case of Pneumocystis carinii pneumonia and cytomegalovirus infection occurring in a previously healthy adult male homosexual who was not receiving known immunosuppressive therapy is described. This 35-year-old man had been treated with metronidazole and tetracycline for an interm
Lancet. 1982 May 15;1(8281):1083-7. Unique Identifier : AIDSLINE MED/82194295
Marmor M; Friedman-Kien AE; Laubenstein L; Byrum RD; William DC; D'onofrio S; Dubin N
An investigation of 20 homosexual men with histologically confirmed Kaposi s sarcoma and 40 controls revealed significant associations between Kaposi s sarcoma and use of a number of drugs (amyl nitrite, ethyl chloride, cocaine, phencyclidine, methaqualone, and amphetamine), history of mononucleosis, and sexual activi
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