Opportunistic infections and immune deficiency in homosexual men. NLM AIDSLINE Important note: Information in this article was accurate in 1982. The state of the art may have changed since the publication date.

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Opportunistic infections and immune deficiency in homosexual men.

Ann Intern Med. 1982 Jun;96(6 Pt 1):700-4. Unique Identifier : AIDSLINE MED/82229062
Mildvan D; Mathur U; Enlow RW; Romain PL; Winchester RJ; Colp C; Singman H; Adelsberg BR; Spigland I

Abstract: A syndrome of opportunistic infections and acquired immune deficiency occurred among four previously healthy homosexual men. Fever, leukopenia, and diminished delayed hypersensitivity were accompanied by various degrees of proctitis, perianal ulcerations, and lymphadenopathy. The infectious agents included Pneumocystis carinii, Cryptococcus neoformans, Candida albicans, herpes simplex virus, and cytomegalovirus. The immune deficiency was characterized as a persistent and profound selective decrease in the function as well as number of T lymphocytes of the helper/inducer subset and a possible activation of the suppressor/cytotoxic subset. Three patients died despite aggressive anti-infective therapy.
Keywords: Adult Case Report Cytomegalovirus Infections/IMMUNOLOGY Fluorescent Antibody Technique Herpes Simplex/IMMUNOLOGY *Homosexuality Human Immunologic Deficiency Syndromes/COMPLICATIONS/*IMMUNOLOGY Infection/ETIOLOGY/*IMMUNOLOGY Male Pneumonia, Pneumocystis carinii/IMMUNOLOGY Sexually Transmitted Diseases/IMMUNOLOGY Support, Non-U.S. Gov't Support, U.S. Gov't, P.H.S. T-Lymphocytes/IMMUNOLOGY JOURNAL ARTICLE

KWDadultcasereportcytomegalovirusinfections/immunologyfluorescentantibodytechniqueherpessimplex/immunologyKWDhomosexualityhumanimmunologicdeficiencysyndromes/complications/KWDimmunologyinfection/etiology/KWDimmunologymalepneumonia,pneumocystiscarinii/immunologysexuallytransmitteddiseases/immunologysupport,non-uKWDsKWDgov'tsupport,uKWDsKWDgov't,pKWDhKWDsKWDt-lymphocytes/immunologyjournalarticle
821030
M82A0007

Copyright © 1982 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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