An outbreak of Pneumocystis carinii pneumonia in homosexual men. NLM AIDSLINE Important note: Information in this article was accurate in 1982. The state of the art may have changed since the publication date.

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An outbreak of Pneumocystis carinii pneumonia in homosexual men.

Ann Intern Med. 1982 Jun;96(6 Pt 1):705-13. Unique Identifier : AIDSLINE MED/82229063
Follansbee SE; Busch DF; Wofsy CB; Coleman DL; Gullet J; Aurigemma GP; Ross T; Hadley WK; Drew WL

Abstract: Pneumocystis carinii pneumonia has rarely been reported in previously healthy persons over the age of 6 months. Five cases of P. carinii pneumonia in adult homosexual men, confirmed by biopsy results, are reported. All five patients were seropositive when tested for antibodies to cytomegalovirus and four had evidence of active concurrent cytomegalovirus infections. Kaposi's sarcoma was shown in two of the patients and one had possible Pneumocystis infection of the central nervous system as well as P. carinii pneumonia. Three patients had second episodes of Pneumocystis pneumonia. Four of the five patients have died. Past or concurrent cytomegalovirus infection and homosexuality were the only common epidemiologic features in all five patients.
Keywords: Adult California Candidiasis, Oral/IMMUNOLOGY Case Report Cytomegalovirus Infections/IMMUNOLOGY *Disease Outbreaks Drug Combinations/THERAPEUTIC USE *Homosexuality Human Immunoglobulins/IMMUNOLOGY Male Pneumonia, Pneumocystis carinii/DRUG THERAPY/EPIDEMIOLOGY/ IMMUNOLOGY/*PATHOLOGY Sexually Transmitted Diseases/IMMUNOLOGY Sulfamethizole/THERAPEUTIC USE T-Lymphocytes/IMMUNOLOGY Trimethoprim/THERAPEUTIC USE JOURNAL ARTICLE

KWDadultcaliforniacandidiasis,oral/immunologycasereportcytomegalovirusinfections/immunologyKWDdiseaseoutbreaksdrugcombinations/therapeuticuseKWDhomosexualityhumanimmunoglobulins/immunologymalepneumonia,pneumocystiscarinii/drugtherapy/epidemiology/immunology/KWDpathologysexuallytransmitteddiseases/immunologysulfamethizole/therapeuticuset-lymphocytes/immunologytrimethoprim/therapeuticusejournalarticle
821030
M82A0006

Copyright © 1982 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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