Szigeti R; Klein E; Masucci MG; Ernberg I; Svedmyr E; Klein G; II. Gyermekklinika, Semmelweis Orvostudomany Egyetem, Budapest,; Hungary
Leukocyte migration inhibition (LMI) elicited by Epstein-Barr virus (EBV) antigens was studied in 13 patients with infectious mononucleosis (IM), 2 patients with chronic mononucleosis, 4 with sex-linked lymphoproliferative disease and in 12 patients with neoplastic diseases (5 with Hodgkin s disease, 6 with
Int Congr Ser; 571:375-379 1982. Unique Identifier : AIDSLINE ICDB/82625235
Sakamoto K; Seeley JK; Purtilo DT; Second Dept. Surgery, Kumamoto Univ. Medical Sch., Kumamoto 860,; Japan
Among conditions that may follow infection with Epstein-Barr virus (EBV), is malignant lymphoma in males affected by the X-linked lymphoproliferative syndrome (XLP). To test the hypothesis that the variable expression of XLP is manifested in obligate carrier females, blood from 12 obligate carrier females was studied
Schreeder MT; Thompson SE; Hadler SC; Berquist KR; Zaidi A; Maynard JE; Ostrow D; Judson FN; Braff EH; Nylund T; Moore JN Jr; Gardner P; Doto IL; Reynolds G
Of 3,816 homosexual men examined in five sexually transmitted disease clinics in the United States , 6.1% had hepatitis B surface antigen, 52.4% had antibody to hepatitis B surface antigen, and 3.0% of the men who had no other indicator of infection with hepatitis B virus (HBV) had anti
Recent reports indicate an increased incidence of Kaposi s sarcoma in young homosexual men. In contrast with the form of the disease seen in the elderly, in which skin involvement is usually confined to the lower extremities, lymph node involvement is rare, and disease progression is relatively slow, Kaposi s sarcoma
Since November 1980 we have diagnosed 11 cases of severe autoimmune thrombocytopenic purpura in homosexual men; their mean platelet count (+/- SE) was 16 000 +/- 3000/mm3. All patients have been sexually active with multiple partners and exposed to numerous viruses and drugs. During this period, we also have diagnosed
Four previously healthy Danish homosexual men developed Kaposi s sarcoma or opportunistic infections with fever of unknown origin and lymphadenopathy. One patient died of a Pneumocystis carinii pneumonia. Three patients had defective cell-mediated immunity with absent leucocyte interferon production and decreased prol
The action of 12-O-tetradecanoylphorbol-13-acetate (TPA) on several retrovirus-related functions was investigated in four virus-host cell systems. The following effects were recorded: (i) in STU-mice, infected with the Friend virus complex (Friend) murine leukaemia virus/Friend spleen focus forming virus) and treated
Extrachromosomal DNA was purified from canine thymus cells acutely infected with different strains of infectious primate type C viruses of the woolly monkey (simian) sarcoma helper virus and gibbon ape leukemia virus group. All DNA preparations contained linear proviral molecules of 9.1 to 9.2 kilobases, at least some
Analyses of 100 subjects with the X-linked lymphoproliferative syndrome (XLP) in 25 kindreds revealed four major interrelated phenotypes: infectious mononucleosis, malignant B-cell lymphoma, aplastic anemia, and hypogammaglobulinemia. Eighty-one of the patients died. Two male subjects were asymptomatic but showed immu
Friedman-Kien AE; Laubenstein LJ; Rubinstein P; Buimovici-Klein E; Marmor M; Stahl R; Spigland I; Kim KS; Zolla-Pazner S
Nineteen cases from an epidemic of disseminated Kaposi s sarcoma in homosexual men were studied by clinical, virologic, immunologic, and genetic methods. The patients were all male homosexuals ranging in age from 29 to 52 years, with histories of multiple sexually transmitted diseases and exposure to both prescription
A syndrome of opportunistic infections and acquired immune deficiency occurred among four previously healthy homosexual men. Fever, leukopenia, and diminished delayed hypersensitivity were accompanied by various degrees of proctitis, perianal ulcerations, and lymphadenopathy. The infectious agents included Pneumocysti
Pneumocystis carinii pneumonia has rarely been reported in previously healthy persons over the age of 6 months. Five cases of P. carinii pneumonia in adult homosexual men, confirmed by biopsy results, are reported. All five patients were seropositive when tested for antibodies to cytom
10 homosexual men with Kaposi s sarcoma (KS) were studied for evidence of cytomegalovirus ( CMV ) infection. IgG and IgM antibodies to CMV were detected in 9 out of 9 and in 7 out of 9 of these patients, respectively. CMV was r
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