Persistent strongyloidiasis in an immunodeficient patient. NLM AIDSLINE Important note: Information in this article was accurate in 1982. The state of the art may have changed since the publication date.

Click here to return to AIDSLINE main menu
DonateNow
Print this Article


Persistent strongyloidiasis in an immunodeficient patient.

Am J Trop Med Hyg. 1982 Jul;31(4):746-51. Unique Identifier : AIDSLINE MED/82254288
Shelhamer JH; Neva FA; Finn DR

Abstract: A 56-year-old woman with acquired, common variable immunodeficiency was found to have persistent gastrointestinal as well as pulmonary infection with Strongyloides stercoralis. Repeated courses of treatment with thiabendazole led to marked reduction or loss of Strongyloides stercoralis larvae, but cessation of treatment always led to recurrence of Strongyloides infection. Several small bowel biopsies showed normal villous architecture and little inflammatory response to presence of larvae. Interestingly, no definite symptomatology could be attributed to the Strongyloides infection. It was postulated that the lack of signs and symptoms of strongyloidiasis, as well as poor response to treatment, was related to the immunodeficiency state. With low-dose, long-term interrupted courses of thiabendazole treatment, the Strongyloides infection finally seemed to be cured.
Keywords: Case Report Feces/PARASITOLOGY Female Human Immunoglobulins/ANALYSIS Immunologic Deficiency Syndromes/*COMPLICATIONS/PARASITOLOGY Intestine, Small/PARASITOLOGY Mebendazole/THERAPEUTIC USE Middle Age Sputum/PARASITOLOGY Strongyloidiasis/*COMPLICATIONS/DRUG THERAPY/IMMUNOLOGY Thiabendazole/THERAPEUTIC USE JOURNAL ARTICLE

KWDcasereportfeces/parasitologyfemalehumanimmunoglobulins/analysisimmunologicdeficiencysyndromes/KWDcomplications/parasitologyintestine,small/parasitologymebendazole/therapeuticusemiddleagesputum/parasitologystrongyloidiasis/KWDcomplications/drugtherapy/immunologythiabendazole/therapeuticusejournalarticle
821130
M82B0010

Copyright © 1982 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

AEGiS is a 501(c)3, not-for-profit, tax-exempt, educational corporation. AEGiS is made possible through unrestricted funding from Boehringer Ingelheim, Bridgestone/Firestone Charitable Trust, Bristol-Myers Squibb Company, Elton John AIDS Foundation, Gill Foundation, the National Library of Medicine, Quest Diagnostics, Roche and Trimeris, and donations from users like you. Always watch for outdated information. This article first appeared in 1982. This material is designed to support, not replace, the relationship that exists between you and your doctor.

AEGiS presents published material, reprinted with permission and neither endorses nor opposes any material. All information contained on this website, including information relating to health conditions, products, and treatments, is for informational purposes only. It is often presented in summary or aggregate form. It is not meant to be a substitute for the advice provided by your own physician or other medical professionals. Always discuss treatment options with a doctor who specializes in treating HIV.

Copyright ©1980, 1982. AEGiS. All materials appearing on AEGiS are protected by copyright as a collective work or compilation under U.S. copyright and other laws and are the property of AEGiS, or the party credited as the provider of the content. .