CELLULAR GENES ANALOGOUS TO RETROVIRAL ONC GENES ARE TRANSCRIBED IN HUMAN TUMOUR CELLS NLM AIDSLINE Important note: Information in this article was accurate in 1982. The state of the art may have changed since the publication date.

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CELLULAR GENES ANALOGOUS TO RETROVIRAL ONC GENES ARE TRANSCRIBED IN HUMAN TUMOUR CELLS

Nature; 295(5845):116-119 1982. Unique Identifier : AIDSLINE ICDB/82605578
Eva A; Robbins KC; Andersen PR; Srinivasan A; Tronick SR; Reddy P; Ellmore NW; Galen AT; Lautenberger JA; Papas TS; Westin EH; Wong-Staal F; Gallo RC; Aaronson SA; Lab. Cellular and Molecular Biology, NCI, NIH, Bethesda, MD,; 20205

Abstract: Polyadenylated RNAs of certain human tumor cell lines are shown to contain transcripts related to the cell-derived transforming onc genes of molecularly cloned primate, murine or avian transforming retrovirus genomes. Thus, analogues of retroviral transforming genes are both present and frequently expressed in human neoplastic cells. (Author abstract) (52 Refs)
Keywords: Abelson Leukemia Virus/GENETICS Animal Cell Line DNA, Neoplasm/GENETICS Mice Mice, Inbred BALB C/MICROBIOLOGY Neoplasms/*GENETICS/MICROBIOLOGY Nucleic Acid Hybridization Retroviridae/*GENETICS RNA, Messenger/*GENETICS RNA, Neoplasm/*GENETICS RNA, Viral/*GENETICS Sarcoma Viruses, Murine/GENETICS Sarcoma Viruses, Simian/GENETICS JOURNAL ARTICLE

KWDabelsonleukemiavirus/geneticsanimalcelllinedna,neoplasm/geneticsmicemice,inbredbalbc/microbiologyneoplasms/KWDgenetics/microbiologynucleicacidhybridizationretroviridae/KWDgeneticsrna,messenger/KWDgeneticsrna,neoplasm/KWDgeneticsrna,viral/KWDgeneticssarcomaviruses,murine/geneticssarcomaviruses,simian/geneticsjournalarticle
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Copyright © 1982 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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