The concurrent application of disulfiram (710 mg/kg diet; or 200 mg/kg diet) effects a strong enhancement of the toxicity and an acceleration of the formation of esophageal tumors by N-methyl-N-nitrosobenzylamine (10 mg/l drinking water) in female SIV 50 rats. Besides that squamous cell papilloma in the trachea and ex
Polyadenylated RNAs of certain human tumor cell lines are shown to contain transcripts related to the cell-derived transforming onc genes of molecularly cloned primate, murine or avian transforming retrovirus genomes. Thus, analogues of retroviral transforming genes are both present and frequently expressed in human n
Mendelian segregation analysis was used to map chromosomal genes for the induction of endogenous N- and B-tropic ecotropic retroviruses (V loci) in high and low leukemic mouse strains. Segregation analysis resulted in the genetic mapping of V loci in six inbred strains to five mouse chromosomes. The V locus of A/J was
Human B-lymphoblast cell lines established from peripheral blood after infection with retroviruses of the simian sarcoma/simian sarcoma associated virus (SSV/SSAV)-gibbon ape leukemia virus (GALV) group generally do not produce detectable virus, even though viral RNA and protein are expressed. We show here by Southern
In a survey of the prevalence of chronic hepatitis B in a male homosexual population, liver biopsies were done in 28 asymptomatic patients who had persistently raised aminotransferases. Four patients had active cirrhosis (AC), 13 had chronic active hepatitis (CAH) of various degrees of severity and 11 had either chron
Ann Parasitol Hum Comp. 1981;56(4):407-21. Unique Identifier : AIDSLINE MED/82111906
Miremad-Gassmann M
Acquired resistance in rats (SIV 50) during infection with 30 Moniliformis moniliformis has an effect on survival, growth and behaviour of the parasite. We observe an expulsion of worms during infection, starting in the 4th week for female worms but usually after 8 weeks for the males. The density of parasites determi
Sirianni MC; Pucillo LP; Fiorilli M; Aiuti F; Banck G; Forsgren A
The mitogenic activity of the formalin-treated bacterial strains Branhamella catarrhalis, Haemophilus influenzae and the Cowan I strain of Staphylococcus aureus was assessed in peripheral blood lymphocytes (PBL) from patients with primary immunodeficiencies, acute lymphocytic leukaemia (ALL), chronic lymphocytic leuke
The immunopathogenesis of 25 kindreds affecting 100 males with the X-linked lymphoproliferative syndrome (XLP) is being studied comprehensively by our registry and laboratory group. XLP is a combined variable immune deficiency with Epstein-Barr virus (EBV) induced phenotypes of: (1) fatal infectious mononucleosis (IM)
Thiel HJ; Matthews T; Broughton E; Butchko A; Bolognesi D
An autologous antiserum against simian sarcoma virus (SSV) nonproducer cells (SSV-NP cells) was characterized by radioimmunoprecipitation. It reacts specifically with two different molecules in SSV-NP cells, a SSV transformation-specific glycoprotein (SSV TrS-gp) and p65, which probably represents a modified gag-precu
Serum samples from 269 men with at least one episode of syphilis were tested for the presence of markers of hepatitis A and B viruses. The patients were divided into three groups: 177 homosexual men, 35 heterosexual men, and 57 men with unknown sexual contacts. The incidence of hepatitis B surface antigen or its antib
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