Cell-mediated immunity in HBeAg-positive homosexuals with chronic liver disease. NLM AIDSLINE Important note: Information in this article was accurate in 1982. The state of the art may have changed since the publication date.

Click here to return to AIDSLINE main menu
DonateNow
Print this Article


Cell-mediated immunity in HBeAg-positive homosexuals with chronic liver disease.

Br J Vener Dis. 1982 Feb;58(1):59-61. Unique Identifier : AIDSLINE MED/82114495
Viola L; Barrison IG; Paradinas F; Coleman JC; Murray-Lyon IM

Abstract: Chronic liver disease developing after infection with the hepatitis B virus may be due to impairment of cell-mediated immunity (CMI). In a study of CMI by the lymphocyte transformation test to two mitogens and hepatitis B surface antigen (HBsAg) the response to the mitogens, phytohemagglutinin (PHA) and purified protein derivative (PPD), was normal in all of 15 male homosexuals with HBsAg-positive chronic liver disease, indicating a normal non-specific cellular immune response. By contrast, only one of the 15 patients showed a response to HBsAg, which may explain the high prevalence of chronic HBsAg carriage in these patients.
Keywords: Adult Chronic Disease Hepatitis B/*IMMUNOLOGY Hepatitis B Surface Antigens/*IMMUNOLOGY Homosexuality Human *Immunity, Cellular Lymphocyte Transformation Male JOURNAL ARTICLE

KWDadultchronicdiseasehepatitisb/KWDimmunologyhepatitisbsurfaceantigens/KWDimmunologyhomosexualityhumanKWDimmunity,cellularlymphocytetransformationmalejournalarticle
820630
M8260013

Copyright © 1982 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

AEGiS is a 501(c)3, not-for-profit, tax-exempt, educational corporation. AEGiS is made possible through unrestricted funding from Boehringer Ingelheim, Bridgestone/Firestone Charitable Trust, Bristol-Myers Squibb Company, Elton John AIDS Foundation, Gill Foundation, the National Library of Medicine, Quest Diagnostics, Roche and Trimeris, and donations from users like you. Always watch for outdated information. This article first appeared in 1982. This material is designed to support, not replace, the relationship that exists between you and your doctor.

AEGiS presents published material, reprinted with permission and neither endorses nor opposes any material. All information contained on this website, including information relating to health conditions, products, and treatments, is for informational purposes only. It is often presented in summary or aggregate form. It is not meant to be a substitute for the advice provided by your own physician or other medical professionals. Always discuss treatment options with a doctor who specializes in treating HIV.

Copyright ©1980, 1982. AEGiS. All materials appearing on AEGiS are protected by copyright as a collective work or compilation under U.S. copyright and other laws and are the property of AEGiS, or the party credited as the provider of the content. .