Diseases associated with immunosuppression. NLM AIDSLINE Important note: Information in this article was accurate in 1982. The state of the art may have changed since the publication date.

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Diseases associated with immunosuppression.

Environ Health Perspect. 1982 Feb;43:9-19. Unique Identifier : AIDSLINE MED/82138718
Heise ER

Abstract: Impairment of any of the major components of the immune system (T-cells, B-cells phagocytes, complement) may result in clinical immunodeficiency. Immune defects can arise from intrinsic or heritable defects of lymphoid elements, failure of normal cellular differentiation, viral infection or other acquired causes. Clinical impairment of immunity is expressed as a marked susceptibility to opportunistic and pathogenic organisms which are difficult to control and by an increased risk of malignancy, allergy and autoimmune disease. Certain immunodeficiency disorders are associated with aberrant immune regulation. The major types of immune deficiency are characterized by unique patterns of infections depending on the level at which the defect occurs and the pathogenic mechanisms of the parasite. The basic defects of representative primary and secondary immunodeficiencies are discussed in relation to observed immunologic consequences.
Keywords: Autoimmune Diseases/IMMUNOLOGY Bacterial Infections/IMMUNOLOGY Cell Differentiation Complement/IMMUNOLOGY Hodgkin's Disease/IMMUNOLOGY Human Immunoglobulins/ANALYSIS Immunologic Deficiency Syndromes/*ETIOLOGY Leukemia, Lymphocytic/IMMUNOLOGY Lymphocytes/IMMUNOLOGY Multiple Myeloma/IMMUNOLOGY Neutrophils/IMMUNOLOGY Phagocytosis Virus Diseases/IMMUNOLOGY JOURNAL ARTICLE REVIEW

KWDautoimmunediseases/immunologybacterialinfections/immunologycelldifferentiationcomplement/immunologyhodgkin'sdisease/immunologyhumanimmunoglobulins/analysisimmunologicdeficiencysyndromes/KWDetiologyleukemia,lymphocytic/immunologylymphocytes/immunologymultiplemyeloma/immunologyneutrophils/immunologyphagocytosisvirusdiseases/immunologyjournalarticlereview
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M8270003

Copyright © 1982 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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