A histologic comparison of hepatitis B with non-A, non-B chronic active hepatitis. NLM AIDSLINE Important note: Information in this article was accurate in 1982. The state of the art may have changed since the publication date.

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A histologic comparison of hepatitis B with non-A, non-B chronic active hepatitis.

Arch Pathol Lab Med. 1982 Sep;106(9):433-6. Unique Identifier : AIDSLINE MED/82283162
Thorne CH; Higgins GR; Ulich TR; Gitnick GL; Lewin KJ

Abstract: The histopathologic aspects of 62 cases of chronic active hepatitis (CAH) were examined to compare hepatitis B surface antigen (HBsAg)-positive with HBsAg-negative (non-A, non-B) cases. Epidemiologically, the two groups were distinct. Homosexuals and young, male users of intravenous drugs accounted for most of the cases of hepatitis B CAH, whereas older men and women with a history of blood transfusions represented a large percentage of the HBsAg-negative cases. However, there were no pathologic differences between the two diseases, in severity of inflammatory activity, degree of architectural damage, appearance of the bile ducts, or prevalence of cirrhosis. In a population of hospitalized patients, these two diseases cannot be distinguished microscopically unless hepatocytes that contain HBsAg are demonstrated. Although our current understanding of non-A, non-B CAH is limited, the disease not necessarily remit spontaneously, and progression to cirrhosis can be expected in some cases.
Keywords: Adult Blood Transfusion/ADVERSE EFFECTS Chronic Disease Comparative Study Hepatitis B/IMMUNOLOGY/*PATHOLOGY Hepatitis B Surface Antigens/ANALYSIS Hepatitis C/IMMUNOLOGY/*PATHOLOGY Hepatitis, Viral, Human/*PATHOLOGY Homosexuality Human Liver/PATHOLOGY Male Middle Age JOURNAL ARTICLE

KWDadultbloodtransfusion/adverseeffectschronicdiseasecomparativestudyhepatitisb/immunology/KWDpathologyhepatitisbsurfaceantigens/analysishepatitisc/immunology/KWDpathologyhepatitis,viral,human/KWDpathologyhomosexualityhumanliver/pathologymalemiddleagejournalarticle
821230
M82C0007

Copyright © 1982 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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