Am J Med. 1982 Aug;73(2):171-8. Unique Identifier : AIDSLINE MED/82281437
Stahl RE; Friedman-Kien A; Dubin R; Marmor M; Zolla-Pazner S
Studies were performed to define the immunologic status of various groups of homosexual men including homosexual men with Kaposi s sarcoma, healthy homosexual men who were of similar ages to the homosexual patients with Kaposi s sarcoma and homosexual men with hyperplastic lymphadenopathy. Heterosexual men with Kaposi
Basic Res Cardiol. 1982 May-Jun;77(3):301-8. Unique Identifier : AIDSLINE MED/82283835
Martorana PA; Gobel H; Kettenbach B; Nitz RE
Various methods used for the assessment of infarct-size were compared in a canine model of coronary artery occlusion. The ability of molsidomine (an antianginal agent) to reduce infarct-size was also investigated. Open-chest dogs underwent occlusion of the left anterior descending coronary artery and starting 30 min a
Eight children, four with combined immunodeficiencies and four with isolated T cell defects were treated with TPI, a crude calf thymic extract. Assessment of response was made on clinical grounds and by monitoring of immune function (T and B cell numbers, immunoglobulin levels, PHA response and delayed cutaneous react
Bene MC; Faure G; Bordigoni P; Olive D; Duheille J
Lymphocytes from five children suffering from ataxia telangectasia or various unclassified immune deficiencies were tested in vitro for their sensitivity to synthetic serum thymic factor (FTS). The percentages of cells bearing T cell markers were elevated after incubation with FTS at graded concentrations (0.25, 2.5 a
To formulate indications for the use of hepatitis B vaccine, we examined the cost effectiveness of three strategies: vaccinating everyone; screening everyone and vaccinating those without evidence of immunity; and neither vaccinating nor screening, but passively immunizing those with known exposure. Estimates of the h
Ann Intern Med. 1982 Sep;97(3):362-6. Unique Identifier : AIDSLINE MED/82282328
Francis DP; Hadler SC; Thompson SE; Maynard JE; Ostrow DG; Altman N; Braff EH; O'Malley P; Hawkins D; Judson FN; Penley K; Nylund T; Christie G; Meyers F; Moore JN Jr; Gardner A; Doto IL; Miller JH; Reynolds GH; Murphy BL; Schable CA; Clark BT; Curran JW; Redeker AG
A randomized, double-blind, vaccine/placebo trial of the Merck 20-micrograms hepatitis B virus (HBV) vaccine was done among 1402 homosexual men attending venereal disease clinics in five American cities. Vaccination was followed by only minimal side effects. Two doses of vaccine induced antibody in 80% of vaccine reci
The histopathologic aspects of 62 cases of chronic active hepatitis (CAH) were examined to compare hepatitis B surface antigen (HBsAg)-positive with HBsAg-negative (non-A, non-B) cases. Epidemiologically, the two groups were distinct. Homosexuals and young, male users of intravenous drugs accounted for most of the cas
Transplantation of allogeneic thymus into thymic deficient individuals will restore T-cell function including ability to demonstrate alloreactivity. In allogeneically reconstituted athymic (nude) mice, alloreactivity as manifested by positive mixed leukocyte reactivity, cell mediated lympholysis and skin graft rejecti
Four cases of Burkitt s-like lymphoma (undifferentiated, monoclonal, B-cell tumours) in homosexual men were seen in a 9-month period in San Francisco. One tumour contained both Epstein-Barr-virus nuclear antigen (EBNA) and cytomegalovirus (
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