Chlamydia trachomatis proctitis. NLM AIDSLINE Important note: Information in this article was accurate in 1981. The state of the art may have changed since the publication date.

Click here to return to AIDSLINE main menu
DonateNow
Print this Article


Chlamydia trachomatis proctitis.

N Engl J Med. 1981 Jul 23;305(4):195-200. Unique Identifier : AIDSLINE MED/81220828
Quinn TC; Goodell SE; Mkrtichian E; Schuffler MD; Wang SP; Stamm WE; Holmes KK

Abstract: One hundreds seventy-one homosexual men, 96 of whom had symptoms suggestive of proctitis and 75 of whom had no such symptoms, were consecutively enrolled in a study of the prevalence, clinical spectrum, and histopathology of Chlamydia trachomatis rectal infections. C. trachomatis was isolated from the rectums of 14 men. Three of the isolates, which had lymphogranuloma venereum (LGV) immunotypes, were recovered from three men with symptoms and signs of severe proctitis, two of whom had granulomatous inflammation that was observed at rectal biopsy and was initially suggestive of Crohn's disease. Eleven isolates, which had non-LGV immunotypes, were obtained from eight symptomatic and three asymptomatic men, all of whom had fecal leukocytes and mild abnormalities of the mucosa present at sigmoidoscopy, usually with mild nongranulomatous inflammatory changes that were seen on rectal biopsy. These observations suggest that the presence of LGV immunotypes of C. trachomatis in the rectum is associated with severe acute proctitis that mimics Crohn's disease of the rectum, whereas the non-LGV immunotypes are associated with a mild proctitis with or without symptoms.
Keywords: Adult Antibodies, Bacterial/ANALYSIS Case Report Chlamydia trachomatis/IMMUNOLOGY/ISOLATION & PURIF Crohn Disease/DIAGNOSIS Diagnosis, Differential Fluorescent Antibody Technique Homosexuality Human Intestinal Mucosa/PATHOLOGY *Lymphogranuloma Venereum/DIAGNOSIS/PATHOLOGY Male Proctitis/DIAGNOSIS/*ETIOLOGY/PATHOLOGY Rectum/MICROBIOLOGY/PATHOLOGY Support, U.S. Gov't, P.H.S. JOURNAL ARTICLE

KWDadultantibodies,bacterial/analysiscasereportchlamydiatrachomatis/immunology/isolation&purifcrohndisease/diagnosisdiagnosis,differentialfluorescentantibodytechniquehomosexualityhumanintestinalmucosa/pathologyKWDlymphogranulomavenereum/diagnosis/pathologymaleproctitis/diagnosis/KWDetiology/pathologyrectum/microbiology/pathologysupport,uKWDsKWDgov't,pKWDhKWDsKWDjournalarticle
811030
M81A0007

Copyright © 1981 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

AEGiS is a 501(c)3, not-for-profit, tax-exempt, educational corporation. AEGiS is made possible through unrestricted funding from Boehringer Ingelheim, Bridgestone/Firestone Charitable Trust, Bristol-Myers Squibb Company, Elton John AIDS Foundation, Gill Foundation, the National Library of Medicine, Quest Diagnostics, Roche and Trimeris, and donations from users like you. Always watch for outdated information. This article first appeared in 1981. This material is designed to support, not replace, the relationship that exists between you and your doctor.

AEGiS presents published material, reprinted with permission and neither endorses nor opposes any material. All information contained on this website, including information relating to health conditions, products, and treatments, is for informational purposes only. It is often presented in summary or aggregate form. It is not meant to be a substitute for the advice provided by your own physician or other medical professionals. Always discuss treatment options with a doctor who specializes in treating HIV.

Copyright ©1980, 1981. AEGiS. All materials appearing on AEGiS are protected by copyright as a collective work or compilation under U.S. copyright and other laws and are the property of AEGiS, or the party credited as the provider of the content. .