Virology and immune mechanisms. NLM AIDSLINE Important note: Information in this article was accurate in 1981. The state of the art may have changed since the publication date.

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Virology and immune mechanisms.

Cancer. 1981 Mar 1;47(5 Suppl):1091-4. Unique Identifier : AIDSLINE MED/81209749
Merigan TC

Abstract: Epstein-Barr virus and hepatitis B virus are two agents which chronically infect man and have been associated with specific neoplasms. Such findings point the way to new methods of control and detection of human malignancies. Furthermore, immunosuppression is another major factor underlying the development of certain malignancies in human populations. It is clear that congenital immunodeficiency states as well as organ transplant recipients requiring iatrogenic immunosuppression and cancer patients requiring chemotherapy and/or x-irradiation are susceptible to particular malignancies at a higher rate than the normal population. Such findings also provide not only clues as to the mechanisms which control tumor development but argue for certain limitations to the extent of immunosuppressive therapy utilized for treatment of cancer.
Keywords: Animal Burkitt's Lymphoma/ETIOLOGY Carcinoma, Hepatocellular/ETIOLOGY Child Hepatitis B Virus Herpesvirus 4, Human Human *Immunity Immunosuppression/*ADVERSE EFFECTS Liver Neoplasms/ETIOLOGY Nasopharyngeal Neoplasms/ETIOLOGY Neoplasms/*ETIOLOGY Papillomavirus Poxviridae Risk Support, U.S. Gov't, P.H.S. Tumor Virus Infections/*EPIDEMIOLOGY JOURNAL ARTICLE

KWDanimalburkitt'slymphoma/etiologycarcinoma,hepatocellular/etiologychildhepatitisbvirusherpesvirus4,humanhumanKWDimmunityimmunosuppression/KWDadverseeffectsliverneoplasms/etiologynasopharyngealneoplasms/etiologyneoplasms/KWDetiologypapillomaviruspoxviridaerisksupport,uKWDsKWDgov't,pKWDhKWDsKWDtumorvirusinfections/KWDepidemiologyjournalarticle
811030
M81A0005

Copyright © 1981 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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