CELLULAR IMMUNITY DEFICIENCY NLM AIDSLINE Important note: Information in this article was accurate in 1981. The state of the art may have changed since the publication date.

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CELLULAR IMMUNITY DEFICIENCY

Int Congr Ser; 502(part1):155-162 1980. Unique Identifier : AIDSLINE ICDB/81611714
Bendixen G; Copenhagen Univ. Hosp., Rigshospitalet, Tagensvej 18, 2200; Copenhagen, Denmark


Abstract: The etiology, diagnosis, monitoring, and therapy of cell-mediated immune deficiency (CMID) is discussed. CMID is a condition in which T-lymphocytes, which are developmentally and functionally dependent on the thymus, are absent or deficient at some level. CMID can be subclassified into two distinct types: the congenital types that result from inborn errors of the T-lymphocyte systems; and the acquired types which are quantitatively more important. Acquired CMID can result from suppression of the T-lymphocyte system due to infection, diseases of the hemopoietic system, malnutrition, or certain chronic diseases such as uremia or cancer. Virus infections, poisons, immunosuppressive drugs, and irradiation also can produce CMID. The pathogenesis of CMID is discussed. One major group of symptoms associated with CMID are those resulting from infection. Diagnostic tests to identify the presence of CMID are described. The importance of immunological monitoring in patients receiving immunosuppressive or cytostatic therapy is discussed. CMID treatment is based on the treatment and prevention of infection. (17 Refs)
Keywords: MEETING PAPER REVIEWKWDmeetingpaperreview
810630
M8160009

Copyright © 1981 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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