Non-Hodgkin's Lymphomas in Children. Graham-Pole J, ed. New York, Masson Publishing USA, Inc., Masson Monographs in Pediatric Hematology/Oncology, 177 pp., 1980.. Unique Identifier : AIDSLINE ICDB/81616020
Leventhal BG; Kaizer H; Oncology Center, Dept. Pediatrics, Johns Hopkins Univ., Sch.; Medicine, 601 N. Broadway, Baltimore, MD, 21205
The potential etiologic role of virus, cytogenetic abnormalities, and immunodeficiency states in non-Hodgkin s lymphoma (NHL) is discussed. Recent observations suggesting that some NHLs represent complex examples of the breakdown of normal immune responses are emphasized. These inc
Two patients had IgA deficiency, giardiasis, and the HLA-B8 antigen. The family of patient 1 included members with juvenile-onset diabetes mellitus, adrenal insufficiency, pernicious anemia, and hypothyroidism, a combination of unusual diseases that has been reported previously to occur as a syndrome with IgA deficien
T lymphocyte subpopulations (T gamma and Tmu) were studied in a group of 36 adult patients with immunodeficiency. Proportions and numbers of Ia(+) T cells were also studied in comparison to 46 normal adult controls. Values for per cent and total numbers of T gamma and Tmu cells indicated no uniform abnormality. Mean n
Basic Life Sci. 1980;15:429-39. Unique Identifier : AIDSLINE MED/81159921
German J
Comparison of the strikingly different distributions of types of cancer that occur in the genetic disorders that feature chromosome instability raises several interesting points. (a) Bloom s syndrome: the distribution suggests that many of the cancers that occur with regularity in the general population just occur mor
Reinherz EL; Geha R; Wohl ME; Morimoto C; Rosen FS; Schlossman SF
We investigated the immune function of a patient with anergy and acquired hypogammaglobulinemia. Despite normal numbers of B cells and T4+ inducer and T5+ suppressor T cells, this patient s lymphocytes did not produce immunoglobulin, proliferate in response to soluble antigens, or generate helper factors in vitro. In
Pallesen G; Hastrup J; Thestrup-Pedersen K; Madsen M
A 6-year-old boy suffered from a severe lymphadenopathy, characterized histologically by a fulminant polyclonal immunoblast proliferation simulating malignant lymphoma with many immunoblasts resembling Reed-Sternberg cells. He had no history of infectious mononucleosis but Epstein-Barr virus (EBV) infection was eviden
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