Induction of syncytia by simian sarcoma virus type I (SSV-I/SSAV-I) in several human transformed cell lines. NLM AIDSLINE Important note: Information in this article was accurate in 1981. The state of the art may have changed since the publication date.

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Induction of syncytia by simian sarcoma virus type I (SSV-I/SSAV-I) in several human transformed cell lines.

Exp Cell Biol. 1980;48(6):421-8. Unique Identifier : AIDSLINE MED/81004786
Ocho M; Ogura H; Tanaka T; Oda T

Abstract: Simian sarcoma virus type I (SSV-I/SSAV-I) induced syncytia formation in human cells derived from malignant tumors (KB, HEp-2 and HeLa cells) and human cells transformed by tumor viruses (RSa, RSb and KC cells) as well as rat XC cells. However, SSV-I/SSAV-I did not induce syncytia formation in human cells derived from normal embryos (WI-38, HEL and HEC). Syncytia-inducing activity of SSV-I/SSAV-I was neutralized by anti-SSV-I/SSAV-I serum, indicating that syncytia formation was SSV-I/SSAV-I mediated.
Keywords: Cell Fusion Cell Line *Cell Transformation, Neoplastic *Cell Transformation, Viral Comparative Study *Cytopathogenic Effect, Viral Hela Cells Human Retroviridae/*PHYSIOLOGY Sarcoma Viruses, Simian/*PHYSIOLOGY JOURNAL ARTICLEKWDcellfusioncelllineKWDcelltransformation,neoplasticKWDcelltransformation,viralcomparativestudyKWDcytopathogeniceffect,viralhelacellshumanretroviridae/KWDphysiologysarcomaviruses,simian/KWDphysiologyjournalarticle
810130
M8110001

Copyright © 1981 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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