[Evaluation of coagulation factor XIII. Critical study of the different techniques used (author's transl)] NLM AIDSLINE Important note: Information in this article was accurate in 1980. The state of the art may have changed since the publication date.

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[Evaluation of coagulation factor XIII. Critical study of the different techniques used (author's transl)]

Pathol Biol (Paris). 1980 May;28(5):313-7. Unique Identifier : AIDSLINE MED/80211272
Soria J; Soria C; Lafay P

Abstract: A critical study of various techniques of factor XIII determination was performed. The method using dansyl-cadaverin seems to be the most sensitive one but not easily usable in routine tests. The biological techniques using factor XIII-free fibrinogen (screening test and classical test) are satisfactory in clinical trials but are not sensitive for the detection of moderate deficiency of factor XIII. The immunological tests used are the electro-immuno-diffusion test and the test of the consumption of an anti-serum. However, only the antibody directed against the sub unit. A must be used. All these techniques were performed in acquired deficiency of factor XIII and a good correlation was obtained. However, in factor XIII congenital deficiency, we propose to associate a biological assay and the antigenic determination of factor XIII in order to detect a possible abnormal factor XIII.
Keywords: Cadaverine/DIAGNOSTIC USE Comparative Study Dansyl Compounds/DIAGNOSTIC USE English Abstract Factor XIII/*ANALYSIS/IMMUNOLOGY Fibrinogen/DIAGNOSTIC USE Human Immune Sera/DIAGNOSTIC USE Immunodiffusion Methods JOURNAL ARTICLEKWDcadaverine/diagnosticusecomparativestudydansylcompounds/diagnosticuseenglishabstractfactorxiii/KWDanalysis/immunologyfibrinogen/diagnosticusehumanimmunesera/diagnosticuseimmunodiffusionmethodsjournalarticle
801030
M80A0004

Copyright © 1980 - National Library of Medicine. Reproduced under license with the National Library of Medicine, Bethesda, MD.

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