Immune deficiency, especially to the Epstein-Barr virus, and increased susceptibility to fatal infectious mononucleosis, acquired agammoglobulinemia, and lymphoma are the cardinal features of the X-linked lymphoproliferative syndrome. Since the establishment of the XLP Registry in September, 1978, 59 affected males in
Several prostatic tissue DNAs have been examined for their content of simian-sarcoma-virus-related sequences. This was done by hybridizing fragmented prostatic DNA with simian sarcoma virus complementary DNA (cDNA) synthesized in vitro. The tissue DNAs contained limited amounts of virus-related sequences. The content
Am J Med. 1980 Mar;68(3):437-40. Unique Identifier : AIDSLINE MED/80150937
Purtilo DT; Paquin LA; Sakamoto K; Hutt LM; Yang JP; Sparling S; Beberman N; McAuley RA
Trauma and blood transfusion led to profound, persistent infectious mononucleosis in a 21 year old man. Splenectomy and trauma had apparently produced transient immune deficiency which was complicated by osteomyelitis of a fractured tibia. The transfused blood probably contained Epstein-Barr virus (EBV). Infectious mo
In four unrelated infants without underlying immunodeficiency, dual infections with cytomegalovirus ( CMV ) and another microorganism developed. The patients included the following: (1) a 3-month-old girl with congenital CMV an
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